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There are 16 words containing M, N, R, S and 3U

UNHUMOROUSunhumorous adj. Not humorous.
UNHUMOROUS adj. not humorous.
UNSLUMBROUSunslumbrous adj. (Archaic, poetic) sleepless.
UNSLUMBROUS adj. not slumbrous.
UNTREMULOUSuntremulous adj. Not tremulous.
UNTREMULOUS adj. not tremulous.
EQUINUMEROUSequinumerous adj. (Mathematics) Having equal cardinality.
EQUINUMEROUS adj. having the same number of members.
NEUROHUMOURSneurohumours n. Plural of neurohumour.
NEUROHUMOUR n. a neurohormone, esp. a neurotransmitter, also NEUROHUMOR.
QUADRUMANOUSquadrumanous adj. Having four feet whose first digits are opposable; applies to all non-human primates.
QUADRUMANOUS adj. of apes, etc., with all four feet adapted for use as hands.
RUMBUNCTIOUSrumbunctious adj. Alternative spelling of rambunctious.
RUMBUNCTIOUS adj. boisterous, unruly, also RAMBUNCTIOUS.
SUPERNACULUMsupernaculum adv. (Obsolete) According to the rules of an old drinking game in which the drinker upturned the empty cup…
supernaculum adv. To the last drop, to the bottom.
supernaculum n. (Obsolete) Excellent wine that one would wish to drink to the last drop.
UNMIRACULOUSunmiraculous adj. Not miraculous; commonplace, mundane.
UNMIRACULOUS adj. not miraculous.
DURALUMINIUMSDURALUMINIUM n. a strong, light, aluminium alloy containing copper, also DURAL, DURALUMIN.
NEUROMUSCULARneuromuscular adj. (Anatomy) Pertaining to the voluntary or reflexive control of muscles by nerves.
NEUROMUSCULAR adj. of or relating to nerves and muscles.
ULTRALUMINOUSultraluminous adj. Very luminous.
UNMISTRUSTFULunmistrustful adj. Not mistrustful.
UNMISTRUSTFUL adj. not mistrustful.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.
UNSURMOUNTABLEunsurmountable adj. (Archaic, rare) insurmountable.
UNSURMOUNTABLE adj. not surmountable.
RUMBUSTIOUSNESSrumbustiousness n. The state or condition of being rumbustious.
RUMBUSTIOUSNESS n. the state of being rumbustious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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