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There are 11 twelve-letter words containing M, P, 3S, T and U

PHYSOSTOMOUSphysostomous adj. (Zoology) Having a duct to the air bladder.
physostomous adj. (Zoology) Relating to the Physostomi.
PHYSOSTOMOUS adj. of fishes, having a duct connecting the air bladder to part of the alimentary canal.
POSTSCENIUMSPOSTSCENIUM n. the part of the stage behind the scenery.
POSTSTIMULUSpoststimulus adj. Following a stimulus.
POSTSTIMULUS adj. following on a stimulus.
SCRIPTURISMSSCRIPTURISM n. adherence to the scriptures.
STUMPINESSESSTUMPINESS n. the state of being stumpy.
SUBOPTIMISESSUBOPTIMISE v. to optimize to an inferior degree, also SUBOPTIMIZE.
SUBSUMPTIONSsubsumptions n. Plural of subsumption.
SUBSUMPTION n. the minor premise of a syllogism.
SUPERSYSTEMSsupersystems n. Plural of supersystem.
SUPERSYSTEM n. a system that is made up of systems.
SUPREMACISTSsupremacists n. Plural of supremacist.
SUPREMACIST n. an advocate or adherent of group supremacy.
SUPREMATISMSSUPREMATISM n. an early 20th century art movement in Russia producing abstract works featuring flat geometric forms.
SUPREMATISTSsuprematists n. Plural of suprematist.
SUPREMATIST n. a practitioner in suprematism.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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