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There are 10 twelve-letter words containing M, 2P, R, 2S and U

APPRESSORIUMappressorium n. (Mycology) A bulbous formation produced by parasitic fungi that is well attached to the cuticle of the…
APPRESSORIUM n. the flattened thickened tip of a hyphal branch by which some parasitic fungi attach to and penetrate their host.
HIPPEASTRUMSHIPPEASTRUM n. any plant of the South American genus Hippeastrum, bulbous, with white or red flowers.
OPPORTUNISMSopportunisms n. Plural of opportunism.
OPPORTUNISM n. the practice of regulating actions by favourable opportunities rather than consistent principles.
PITTOSPORUMSpittosporums n. Plural of pittosporum.
PITTOSPORUM n. any of numerous chiefly subtropical evergreen shrubs or small trees.
PRESUMPTIONSpresumptions n. Plural of presumption.
PRESUMPTION n. the act of presuming.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PSEUDOMORPHSpseudomorphs n. Plural of pseudomorph.
PSEUDOMORPH n. a false or abnormal physical form.
SUPERIMPOSEDsuperimposed v. Simple past tense and past participle of superimpose.
superimposed adj. Positioned on or above something else, especially in layers; superposed.
superimposed adj. (Geology) layered or stratified.
SUPERIMPOSESsuperimposes v. Third-person singular simple present indicative form of superimpose.
SUPERIMPOSE v. to place or lay over or above something.
SUPPORTMENTSsupportments n. Plural of supportment.
SUPPORTMENT n. support.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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