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There are 4 twelve-letter words containing 2M, O, P and 3S

ISOMORPHISMSisomorphisms n. Plural of isomorphism.
ISOMORPHISM n. similarity in shape or structure in unrelated forms.
PLASMODESMASplasmodesmas n. Plural of plasmodesma.
PLASMODESMA n. a strand of living cytoplasm connecting two cells, also PLASMODESM.
POLYMASTISMSPOLYMASTISM n. the presence of supernumerary breasts or nipples, also POLYMASTIA, POLYMASTY.
SOMATOPLASMSsomatoplasms n. Plural of somatoplasm.
SOMATOPLASM n. protoplasm of the somatic cells.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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