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There are 19 twelve-letter words containing 2M, O, P, R and U

AUTOMORPHISMautomorphism n. (Algebra) An isomorphism of a mathematical object or system of objects onto itself.
automorphism n. The ascription to others of one’s own characteristics.
AUTOMORPHISM n. ascription to others of one's own characteristics.
COMPUTERDOMSCOMPUTERDOM n. the world of computers.
CUPRAMMONIUMcuprammonium n. (Inorganic chemistry) Synonym of cuproammonium.
CUPRAMMONIUM n. a solution of cupric hydroxide in ammonia.
HOMOMORPHOUShomomorphous adj. Characterized by homomorphism.
HOMOMORPHOUS adj. alike in form, esp. if essentially different otherwise.
LITHOSPERMUMlithospermum n. (Botany) Any plant of the genus Lithospermum.
Lithospermum prop.n. A taxonomic genus within the family Boraginaceae – the stoneseeds and gromwells.
LITHOSPERMUM n. a kind of flower.
MESOMORPHOUSmesomorphous adj. Mesomorphic.
MESOMORPHOUS adj. relating to a mesomorph.
METACOMPUTERMETACOMPUTER n. a collection of computers that looks and functions like a single computer.
METAMORPHOUSmetamorphous adj. Metamorphic.
METAMORPHOUS adj. of or relating to metamorphosis (especially of rocks).
MINICOMPUTERminicomputer n. (Computer hardware) A computer smaller than a mainframe, but larger than a microcomputer.
MINICOMPUTER n. a small computer that is intermediate between a microcomputer and a mainframe.
MONOMORPHOUSmonomorphous adj. Monomorphic.
MONOMORPHOUS adj. existing in one form only.
MONOSPERMOUSmonospermous adj. (Botany) Having only one seed.
MONOSPERMOUS adj. producing only one seed, also MONOSPERMAL.
MULTIPROBLEMmultiproblem adj. Involving more than one problem.
MULTIPROBLEM adj. featuring many problems.
PRASEODYMIUMpraseodymium n. A chemical element (symbol Pr) with an atomic number of 59, a soft, silvery, malleable and ductile metal…
PRASEODYMIUM n. a chemical element, a metal with green salts, isolated from the once-supposed element didymium.
PROGYMNASIUMprogymnasium n. In Germany, a classical school without the higher classes; a school preparatory to a gymnasium.
PROGYMNASIUM n. in Germany, a gymnasium for pupils up to age 16 only, at which university entrance qualifications are not obtainable.
PROTHALAMIUMprothalamium n. Alternative form of prothalamion.
PROTHALAMIUM n. (Spenser) a song in honour of a marriage, also PROTHALAMION.
RUMGUMPTIONSRUMGUMPTION n. (Scots) common sense, also RUMBLEGUMPTION, RUMELGUMPTION, RUMLEGUMPTION, RUMMELGUMPTION, RUMMLEGUMPTION.
SPERMAGONIUMspermagonium n. (Lichenology) Alternative spelling of spermogonium.
SPERMAGONIUM n. a receptacle in which spermatia are produced in some fungi and lichens.
SPERMOGONIUMspermogonium n. (Lichenology) A conceptacle of certain lichens, containing spermatia.
SPERMOGONIUM n. a flask-shaped structure in some fungi, also SPERMOGONE.
UNPROGRAMMEDunprogrammed adj. Not programmed.
unprogrammed adj. (Quakerism) Having religious services that take the form of silent group meditation.
UNPROGRAMMED adj. not programmed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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