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There are 12 ten-letter words containing 2M, O and 3S

COMMISSARScommissars n. Plural of commissar.
COMMISSAR n. the head of a government department in the USSR.
DESMOSOMESdesmosomes n. Plural of desmosome.
DESMOSOME n. a small thickened patch on the membrane of a cell.
EMBLOSSOMSemblossoms v. Third-person singular simple present indicative form of emblossom.
EMBLOSSOM v. to cover or adorn with blossoms.
IMMISSIONSimmissions n. Plural of immission.
IMMISSION n. insertion; infusion.
ISOMERISMSisomerisms n. Plural of isomerism.
ISOMERISM n. the state, quality, or relation, of two or more isomeric substances.
MASOCHISMSmasochisms n. Plural of masochism.
MASOCHISM n. the derivation of sexual gratification from the suffering of pain.
MASSYMORESmassymores n. Plural of massymore.
MASSYMORE n. (Scott) a subterranean prison, also MATTAMORE.
MISHMOSHESmishmoshes n. Plural of mishmosh.
MISHMOSH n. a confused mixture, also MISHMASH.
MISONEISMSmisoneisms n. Plural of misoneism.
MISONEISM n. a hatred or fear of change or innovation.
MOSAICISMSmosaicisms n. Plural of mosaicism.
MOSAICISM n. the property or state of being composed of cells of two genetically different types.
SYMBOLISMSsymbolisms n. Plural of symbolism.
SYMBOLISM n. the use of symbols in literature or art.
SYMPOSIUMSsymposiums n. Plural of symposium.
SYMPOSIUM n. (Greek) a conference.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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