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There are 15 words containing 2M, 2S and X

AXISYMMETRIESaxisymmetries n. Plural of axisymmetry.
AXISYMMETRY n. the state of being axisymmetric.
EXTREMISMSextremisms n. Plural of extremism.
EXTREMISM n. the taking of an extreme position.
HEXAMERISMSHEXAMERISM n. the state of being hexamerous.
HOMOSEXUALISMhomosexualism n. (Dated) Homosexuality, the state of being homosexual.
homosexualism n. (Derogatory) A purported ideology behind (and promoting) homosexuality; gayness viewed as an ideology…
HOMOSEXUALISM n. being homosexual.
HOMOSEXUALISMSHOMOSEXUALISM n. being homosexual.
MAXIMALISTSmaximalists n. Plural of maximalist.
Maximalists n. Plural of Maximalist.
MAXIMALIST n. a revolutionary, a Bolshevik.
MAXIMISATIONSmaximisations n. Plural of maximisation.
MAXIMISATION n. the act of maximising, also MAXIMATION, MAXIMIZATION.
MAXIMISERSmaximisers n. Plural of maximiser.
MAXIMISER n. one who maximises, also MAXIMIZER.
MAXIMISESmaximises v. Third-person singular simple present indicative form of maximise.
MAXIMISE v. to make as great as possible, also MAXIMIZE.
MAXIMISTSMAXIMIST n. a habitual maker of maxims.
MAXIMUSESMAXIMUS n. a very long bell ringing sequence on twelve bells.
MIXMASTERSmixmasters n. Plural of mixmaster.
MIXMASTER n. a disc jockey.
MYXOMATOSESMYXOMATOSIS n. a fatal contagious disease of rabbits.
MYXOMATOSISmyxomatosis n. A usually fatal viral disease of rabbits, causing skin tumors.
myxomatosis n. In general, a condition characterized by the growth of many myxomata (tumors of primitive connective tissue).
MYXOMATOSIS n. a fatal contagious disease of rabbits.
XYLOBALSAMUMSXYLOBALSAMUM n. the dried twigs, or the wood, of the balm of Gilead tree.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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