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There are 7 eight-letter words containing 2M and 3O

HOMEROOMhomeroom n. (US) A classroom where school pupils of the same age gather for registration, or for other purposes…
homeroom n. (US) The collection of pupils who gather in such a room.
HOMEROOM n. the classroom where pupils gather before class.
MOKOMOKOMOKOMOKO n. (Maori) a type of skink found in New Zealand.
MONOMODEmonomode adj. Capable of operation only in a single mode.
MONOMODE adj. designating a very fine optical fibre (less than 10 micrometres in diameter), used in telecommunications.
MONOSOMEmonosome n. The chromosome whose homologous counterpart is missing in monosomy.
MONOSOME n. an unpaired chromosome.
MONOSOMYmonosomy n. A genetic disorder with the presence of only one chromosome (instead of the typical two in humans) from a pair.
MONOSOMY n. a condition of having one unpaired chromosome.
MOTORDOMmotordom n. The realm or sphere of motor cars; motoring generally.
MOTORDOM n. the motor vehicle industry.
ROOMSOMEroomsome adj. (Archaic) Characterised or marked by room or roominess; spacious.
ROOMSOME adj. (obsolete) roomy.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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