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There are 9 five-letter words containing M, O, T and U

MOTUSmotus n. Plural of motu.
MOTU n. (Maori) a small reef island.
MOULTmoult n. The process of shedding or losing a covering of fur, feathers or skin etc.
moult n. The skin or feathers cast off during the process of moulting.
moult v. (Intransitive) To shed or lose a covering of hair or fur, feathers, skin, horns, etc, and replace it with a fresh one.
MOUNTmount n. A hill or mountain.
mount n. (Palmistry) Any of seven fleshy prominences in the palm of the hand, taken to represent the influences…
mount n. (Obsolete) A bulwark for offence or defence; a mound.
MOUSTMOUST n. (Scots) a musk, hair-powder.
MOUST v. to powder, also MUIST.
MOUTHmouth n. (Anatomy) The opening of a creature through which food is ingested.
mouth n. The end of a river out of which water flows into a sea or other large body of water.
mouth n. An outlet, aperture or orifice.
MUTONmuton n. (Genetics) A unit of mutation forming part of a recon.
MUTON n. a unit of nucleic acid.
NOTUMnotum n. (Zoology) The back; the dorsal aspect of the thorax in insects.
NOTUM n. (Greek) part of the thorax of an insect.
SMOUTsmout n. (Dated, slang) A printer who does short-term work in various offices.
smout v. (Dated, intransitive) To do occasional work.
SMOUT v. (Scots) to work as a compositor doing odd jobs, also SMOOT.
TUMORtumor n. (Oncology, pathology) An abnormal growth; differential diagnosis includes abscess, metaplasia, and neoplasia.
TUMOR n. (US) an abnormal swelling or enlargement, now esp. a new growth of cells in the body without inflammation, also TUMOUR.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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