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There are 16 words containing L, 2N, 2P, S and U

NONPURPOSEFULnonpurposeful adj. Not purposeful.
PANLEUCOPENIASPANLEUCOPENIA n. a viral disease of cats marked by a deficiency of white blood cells, also PANLEUKOPENIA.
PANLEUKOPENIASpanleukopenias n. Plural of panleukopenia.
PANLEUKOPENIA n. a viral disease of cats marked by a deficiency of white blood cells, also PANLEUCOPENIA.
SULPHINPYRAZONEsulphinpyrazone n. Alternative form of sulfinpyrazone.
SULPHINPYRAZONE n. a drug used to treat gout.
SUPPLANTATIONsupplantation n. The act of supplanting.
supplantation n. The condition of having been displaced.
SUPPLANTATION n. the act of supplanting.
SUPPLANTATIONSsupplantations n. Plural of supplantation.
SUPPLANTATION n. the act of supplanting.
SUPPLANTINGsupplanting v. Present participle of supplant.
SUPPLANT v. to take the place of.
SUPPLEMENTATIONsupplementation n. The act of supplementing.
supplementation n. Something added as a supplement.
SUPPLEMENTATION n. the act of supplementing.
SUPPLEMENTINGsupplementing v. Present participle of supplement.
SUPPLEMENT v. to add or serve as a supplement to.
UNAPPETISINGLYunappetisingly adv. Alternative spelling of unappetizingly.
UNAPPETISING adv. not appetising.
UNAPPREHENSIBLEunapprehensible adj. Alternative form of inapprehensible.
UNAPPREHENSIBLE adj. not apprehensible.
UNDERSUPPLYINGundersupplying v. Present participle of undersupply.
UNDERSUPPLY v. to supply too little.
UNFLAPPABLENESSunflappableness n. (Rare) Unflappability.
UNFLAPPABLENESS n. the state of being unflappable.
UNSLIPPINGunslipping adj. That does not slip.
UNSLIPPING adj. not slipping.
UNSUPPLENESSunsuppleness n. The quality of not being supple.
UNSUPPLENESS n. the state of being unsupple.
UNSUPPLENESSESUNSUPPLENESS n. the state of being unsupple.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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