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There are 18 words containing 2L, P, 2S and 2U

SULPHURYLSsulphuryls n. Plural of sulphuryl.
SULPHURYL n. a particular chemical divalent group, also SULFONYL, SULFURYL, SULPHONYL.
SCRUPULOUSLYscrupulously adv. In a careful manner, with scruple; done with careful attention to detail.
SCRUPULOUS adv. having moral integrity, acting in strict regard for what is considered right or proper.
SUBMULTIPLESsubmultiples n. Plural of submultiple.
SUBMULTIPLE n. a quantity that divides into another exactly.
SULPHUROUSLYsulphurously adv. Alternative spelling of sulfurously.
SULPHUROUS adv. containing sulphur in lower valency; pertaining to hellfire, also SULFUROUS.
PRECALCULUSESPRECALCULUS n. a mathematical prerequisite for the study of calculus.
PUSILLANIMOUSpusillanimous adj. Showing ignoble cowardice, or contemptible timidity.
PUSILLANIMOUS adj. lacking courage, timid.
SULPHUREOUSLYsulphureously adv. Archaic form of sulfurously.
SULPHUREOUS adv. pertaining to or like sulphur, also SULFUREOUS.
SUPERFLUOUSLYsuperfluously adv. In a superfluous manner.
SUPERFLUOUS adv. extraneous.
SUSPENSEFULLYsuspensefully adv. In a suspenseful manner.
SUSPENSEFUL adv. full of suspense.
UNHELPFULNESSunhelpfulness n. The state of being unhelpful.
UNHELPFULNESS n. the quality of being unhelpful.
LIPOSCULPTURESLIPOSCULPTURE n. cosmetic surgery on the lips.
SULPHONYLUREASsulphonylureas n. Plural of sulphonylurea.
SULPHONYLUREA n. a synthetic compound used to reduce the level of glucose in the blood in diabetes mellitus.
SUPERCILIOUSLYsuperciliously adv. In a supercilious manner.
SUPERCILIOUS adv. haughtily contemptuous.
SUPRAMOLECULESsupramolecules n. Plural of supramolecule.
SUPRAMOLECULE n. a cluster of molecules, usually created artificially.
UNSCRUPULOUSLYunscrupulously adv. In an unscrupulous manner.
UNSCRUPULOUS adv. not scrupulous.
PUSILLANIMOUSLYpusillanimously adv. In a pusillanimous manner.
PUSILLANIMOUS adv. lacking courage, timid.
SCULPTURESQUELYsculpturesquely adv. In a sculpturesque manner.
SCULPTURESQUE adv. done in the manner of or resembling sculpture.
UNHELPFULNESSESunhelpfulnesses n. Plural of unhelpfulness.
UNHELPFULNESS n. the quality of being unhelpful.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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