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There are 3 twelve-letter words containing 2L, 2O, 2P and R

PROPRANOLOLSpropranolols n. Plural of propranolol.
PROPRANOLOL n. a beta-blocker drug used mainly in the treatment of cardiac arrhythmia.
PROTOPLASMALprotoplasmal adj. (Cytology) Of or relating to protoplasm.
PROTOPLASMAL adj. of or like protoplasm, also PROTOPLASMATIC, PROTOPLASMIC, PROTOPLASTIC.
WHIPPOORWILLwhippoorwill n. A nocturnal insectivorous bird of North America (Antrostomus vociferus, syn. Caprimulgus vociferus)…
whippoorwill n. The distinct call of the above bird.
whip-poor-will n. Alternative form of whippoorwill (Antrostomus vociferus).

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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