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There are 17 twelve-letter words containing L, M, 2P and 2S

AMPELOPSISESampelopsises n. Plural of ampelopsis.
AMPELOPSIS n. a woody vine.
EPISCOPALISMEPISCOPALISM n. episcopalian government and doctrine.
MALAPROPISMSmalapropisms n. Plural of malapropism.
MALAPROPISM n. a humorous misuse of a word, also MALAPROP.
MALAPROPISTSmalapropists n. Plural of malapropist.
MALAPROPIST n. one who commits malapropisms.
MILKSOPPIESTMILKSOPPY adj. like a milksop, a spiritless man or youth, also MILKSOPPING.
MISAPPRAISALmisappraisal n. A bad or inaccurate appraisal.
MISAPPRAISAL n. a wrong appraisal.
PAMPELMOOSESpampelmooses n. Plural of pampelmoose.
PAMPELMOOSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUS, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
PAMPELMOUSESpampelmouses n. Plural of pampelmouse.
PAMPELMOUSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, POMELO, POMPELMOOSE, POMPELMOUS, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
PHILOSOPHISMphilosophism n. Spurious philosophy; the love or practice of sophistry.
PHILOSOPHISM n. would-be philosophy.
PHYTOPLASMASphytoplasmas n. Plural of phytoplasma.
PIMPLINESSESPIMPLINESS n. the state of being pimply.
PLOWMANSHIPSPLOWMANSHIP n. the craft of the plowman, also PLOUGHMANSHIP.
POMPELMOOSESpompelmooses n. Plural of pompelmoose.
POMPELMOOSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOUS, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
POMPELMOUSESpompelmouses n. Plural of pompelmous.
pompelmouses n. Plural of pompelmouse.
POMPELMOUSE n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUS, POMPELO, PUMELO, PUMMELO.
PSAMMOPHILESpsammophiles n. Plural of psammophile.
PSAMMOPHILE n. a sand-loving plant, also PSAMMOPHIL.
SPERMOPHILESspermophiles n. Plural of spermophile.
SPERMOPHILE n. a member of family of seed-loving rodents.
TROPHOPLASMStrophoplasms n. Plural of trophoplasm.
TROPHOPLASM n. the nutritive substance of cell.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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