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There are 8 twelve-letter words containing 2L, O, 2P and U

PODOPHYLLUMSpodophyllums n. Plural of podophyllum.
PODOPHYLLUM n. the dried rootlet and rhizome of the mayapple, used as a caustic.
POLYPETALOUSpolypetalous adj. (Botany) having a corolla composed of distinct, separable petals.
POLYPETALOUS adj. separate petals.
POLYPHYLLOUSpolyphyllous adj. (Botany) Having many leaves (or flowers).
POLYPHYLLOUS adj. having the perianth leaves free.
POLYSEPALOUSpolysepalous adj. (Botany, of a calyx) having separate sepals.
POLYSEPALOUS adj. having separate sepals.
POLYSULPHIDEpolysulphide n. (Chemistry) Alternative spelling of polysulfide.
POLYSULPHIDE n. a sulfide containing two or more atoms of sulfur in the molecule, also POLYSULFIDE.
POPULATIONALpopulational adj. Of or pertaining to population.
POPULATIONAL adj. relating to population.
PURPOSEFULLYpurposefully adv. In a purposeful manner.
purposefully adv. (Proscribed) On purpose, purposely, deliberately.
PURPOSEFUL adv. showing purpose.
SUPPLETORILYSUPPLETORY adv. supplemental, also SUPPLETIVE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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