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There is only one eight-letter word containing L, N, P and 2R

PRERENALprerenal adj. Situated above the kidneys, or at the junction of the vena cava and the renal vein.
prerenal adj. Occurring in the blood supply to the kidneys.
PRERENAL adj. situated in front of the kidneys.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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