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There are 12 words containing I, R, 4S, T and Y

SYSTEMISERSsystemisers n. Plural of systemiser.
SYSTEMISER n. one who systemises, also SYSTEMIZER.
RESISTLESSLYresistlessly adv. (Archaic, chiefly literary) In an unresisting manner; without objection or opposition.
RESISTLESS adv. (archaic) irresistible.
SYNTHESISERSsynthesisers n. Plural of synthesiser.
SYNTHESISER n. a person who, or thing which, synthesizes, also SYNTHESIZER.
RESYNTHESISESresynthesises v. Third-person singular simple present indicative form of resynthesise.
RESYNTHESISE v. to synthesise again, also RESYNTHESIZE.
SARCOCYSTISESSARCOCYSTIS n. a sporozoan of the genus Sarcocystis, parasitic in muscles of mammals.
SYSTEMATISERSsystematisers n. Plural of systematiser.
SYSTEMATISER n. one who systematises, also SYSTEMATIZER.
HYPEROSTOSISESHYPEROSTOSIS n. abnormal growth of bone tissue.
MYSTERIOUSNESSmysteriousness n. The quality of being mysterious.
MYSTERIOUSNESS n. the state of being mysterious.
RESYSTEMATISESRESYSTEMATISE v. to systematise again, also RESYSTEMATIZE.
ASTROPHYSICISTSastrophysicists n. Plural of astrophysicist.
ASTROPHYSICIST n. a student of astrophysics.
HYPERSENSITISEShypersensitises v. Third-person singular simple present indicative form of hypersensitise.
HYPERSENSITISE v. to make hypersensitive, also HYPERSENSITIZE.
SCHOOLMISTRESSYschoolmistressy adj. Resembling or characteristic of a schoolmistress.
SCHOOLMISTRESSY adj. like a schoolmistress, prim.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 128 words
  • Scrabble in French: 66 words
  • Scrabble in Spanish: 1 word
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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