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There are 15 fifteen-letter words containing I, O, 4S and 2T

ASSOCIATIONISTSassociationists n. Plural of associationist.
ASSOCIATIONIST n. one who believes in the theory of associationism.
ASTROPHYSICISTSastrophysicists n. Plural of astrophysicist.
ASTROPHYSICIST n. a student of astrophysics.
BIOSYSTEMATISTSbiosystematists n. Plural of biosystematist.
BIOSYSTEMATIST n. one who studies biosystematics.
DISSOLUTIONISTSdissolutionists n. Plural of dissolutionist.
DISSOLUTIONIST n. a proponent of dissolutionism.
DISTORTEDNESSESDISTORTEDNESS n. the state of being distorted.
MASSOTHERAPISTSmassotherapists n. Plural of massotherapist.
MASSOTHERAPIST n. one who practises massotherapy, therapy using massage.
OBSTINATENESSESobstinatenesses n. Plural of obstinateness.
OBSTINATENESS n. OBSTINATE, stubborn.
PHOTOSENSITISESphotosensitises v. Third-person singular simple present indicative form of photosensitise.
PHOTOSENSITISE v. to make photosensitive by chemical or other means, also PHOTOSENSITIZE.
POSTMASTERSHIPSpostmasterships n. Plural of postmastership.
POSTMASTERSHIP n. the office of postmaster.
SENSATIONALISTSsensationalists n. Plural of sensationalist.
SENSATIONALIST n. one who engages in sensationalism.
SENTENTIOUSNESSsententiousness n. The state or condition of being sententious.
SENTENTIOUSNESS n. the state of being sententious.
SPECTROSCOPISTSspectroscopists n. Plural of spectroscopist.
SPECTROSCOPIST n. one who uses a spectroscope.
SYNTHESISATIONSSYNTHESISATION n. the process of synthesising, also SYNTHESIZATION.
TOASTMISTRESSEStoastmistresses n. Plural of toastmistress.
TOASTMISTRESS n. a woman who acts as toastmaster.
TRANSFUSIONISTStransfusionists n. Plural of transfusionist.
TRANSFUSIONIST n. a doctor who performs transfusions.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 46 words
  • Scrabble in French: 43 words
  • Scrabble in Spanish: 11 words
  • Scrabble in Italian: 30 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 1 word


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