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There are 6 twelve-letter words containing I, 2M, 2O, 2S and U

AMPHISTOMOUSamphistomous adj. (Zoology) Having a sucker at each extremity.
AMPHISTOMOUS adj. having a sucker at either end, as some worms.
MESOTHORIUMSmesothoriums n. Plural of mesothorium.
MESOTHORIUM n. an old name for either of two radioactive elements.
MICROSTOMOUSMICROSTOMOUS adj. having an unusually small mouth, also MICROSTOMATOUS.
MUSHROOMIESTMUSHROOMY adj. of or like a mushroom.
MUSHROOMINGSmushroomings n. Plural of mushrooming.
MUSHROOMING n. rapid growth.
SOMNILOQUISMsomniloquism n. The act or habit of talking in one’s sleep.
SOMNILOQUISM n. talking in one's sleep.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 12 words
  • Scrabble in French: 4 words
  • Scrabble in Spanish: 16 words
  • Scrabble in Italian: 20 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 2 words


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