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There are 15 fifteen-letter words containing 2I, 2O, R, 2S and Y

DERMATOMYOSITISdermatomyositis n. A disease of connective tissue, related to polymyositis, characterized by inflammation of the muscles and skin.
DERMATOMYOSITIS n. a disease characterized by inflammation of the skin and muscles, and wasting of the muscles.
DISHARMONIOUSLYdisharmoniously adv. In a disharmonious manner.
DISHARMONIOUS adv. lacking in harmony.
HYDROBIOLOGISTShydrobiologists n. Plural of hydrobiologist.
HYDROBIOLOGIST n. a student of hydrobiology.
HYPOCHONDRIASIShypochondriasis n. (Medicine) A mental disorder characterized by excessive fear of or preoccupation with a serious illness…
HYPOCHONDRIASIS n. morbid concern about one's health esp. when accompanied by delusions of physical disease.
HYPOTHYROIDISMShypothyroidisms n. Plural of hypothyroidism.
HYPOTHYROIDISM n. deficient activity of the thyroid gland.
LIPODYSTROPHIESlipodystrophies n. Plural of lipodystrophy.
LIPODYSTROPHY n. a medical condition characterized by abnormal or degenerative conditions of the body's adipose tissue.
MYRISTICIVOROUSMYRISTICIVOROUS adj. feeding upon nutmegs.
POLYMERISATIONSpolymerisations n. Plural of polymerisation; alternative spelling of polymerizations.
POLYMERISATION n. a chemical reaction in which two or more molecules combine to form larger molecules that contain repeating structural units, also POLYMERIZATION.
PROSELYTISATIONproselytisation n. Alternative spelling of proselytization.
PROSELYTISATION n. the act of proselytising, also PROSELYTIZATION.
PSYCHOHISTORIANpsychohistorian n. One who is involved in the field of psychohistory.
PSYCHOHISTORIAN n. a student of psychohistory.
PSYCHOHISTORIESpsychohistories n. Plural of psychohistory.
PSYCHOHISTORY n. historical analysis or interpretation using psychological and psychoanalytic methods.
PYRAMIDOLOGISTSpyramidologists n. Plural of pyramidologist.
PYRAMIDOLOGIST n. a specialist in pyramidology.
STRONGYLOIDOSISstrongyloidosis n. (Pathology) A disease caused by infection by roundworms of the superfamily Strongyloidea.
STRONGYLOIDOSIS n. an intestinal disease caused by infestation with a type of threadworm.
SYNCHRONISATIONsynchronisation n. Non-Oxford British spelling standard spelling of synchronization.
SYNCHRONISATION n. the act of synchronising, also SYNCHRONIZATION.
TRYPANOSOMIASIStrypanosomiasis n. (Pathology) Any of several diseases or infections caused by a trypanosome.
TRYPANOSOMIASIS n. infection with or disease caused by trypanosomes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 88 words
  • Scrabble in French: 14 words
  • Scrabble in Spanish: 2 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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