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There are 12 words containing I, O, S, 3T and X

TETROTOXINSTETROTOXIN n. a deadly nerve poison found in a species of Japanese puffer fish, also TETRODOTOXIN.
EXTORTIONISTextortionist n. Someone who extorts; an extortioner.
EXTORTIONIST n. one who practises extortion.
EXTORTIONISTSextortionists n. Plural of extortionist.
EXTORTIONIST n. one who practises extortion.
OTOTOXICITIESototoxicities n. Plural of ototoxicity.
OTOTOXICITY n. the state of being ototoxic.
TETRODOTOXINStetrodotoxins n. Plural of tetrodotoxin.
TETRODOTOXIN n. a deadly nerve poison found in a species of Japanese puffer fish, also TETROTOXIN.
CYTOTAXONOMISTcytotaxonomist n. One who studies cytotaxonomy.
CYTOTAXONOMIST n. a practitioner of cytotaxonomy.
CYTOTOXICITIEScytotoxicities n. Plural of cytotoxicity.
CYTOTOXICITY n. the quality of being cytotoxic.
CYTOTAXONOMISTScytotaxonomists n. Plural of cytotaxonomist.
CYTOTAXONOMIST n. a practitioner of cytotaxonomy.
DEXTROROTATIONSdextrorotations n. Plural of dextrorotation.
DEXTROROTATION n. rotation to the right.
PHOTOTOXICITIESphototoxicities n. Plural of phototoxicity.
PHOTOTOXICITY n. the state of being phototoxic.
PHYTOTOXICITIESphytotoxicities n. Plural of phytotoxicity.
PHYTOTOXICITY n. the state of being phytotoxic.
TEXTUALIZATIONStextualizations n. Plural of textualization.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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