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There are 12 words containing I, M, R, 2S, U and X

BRUXISMSbruxisms n. Plural of bruxism.
BRUXISM n. a nervous grinding of the teeth.
INTERSEXUALISMintersexualism n. The state of being intersexual.
INTERSEXUALISM n. the state of being intersexual, existing between sexes.
INTERSEXUALISMSINTERSEXUALISM n. the state of being intersexual, existing between sexes.
MYXOVIRUSESmyxoviruses n. Plural of myxovirus.
MYXOVIRUS n. any of a group of related viruses causing influenza, mumps etc.
PARAMYXOVIRUSESparamyxoviruses n. Plural of paramyxovirus.
PARAMYXOVIRUS n. any of a group of viruses which includes the mumps and measles viruses.
SUBMATRIXESsubmatrixes n. Plural of submatrix.
SUBMATRIX n. part of a matrix.
SUBMAXILLARIESSUBMAXILLARY n. the submaxillary gland.
TRANSEXUALISMTRANSEXUALISM n. a strong desire to change sex.
TRANSEXUALISMSTRANSEXUALISM n. a strong desire to change sex.
TRANSSEXUALISMtranssexualism n. Transsexuality; the state of being transsexual.
TRANSSEXUALISM n. the state of being a transsexual.
TRANSSEXUALISMSTRANSSEXUALISM n. the state of being a transsexual.
XIPHISTERNUMSxiphisternums n. Plural of xiphisternum.
XIPHISTERNUM n. the posterior and smallest of the three divisions of the sternum.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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