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There are 8 eight-letter words containing I, M, R, S, 2T and U

MISTRUSTmistrust n. Lack of trust or confidence; distrust, untrust.
mistrust v. (Transitive) To have no confidence in (something or someone).
mistrust v. (Transitive) To be wary, suspicious or doubtful of (something or someone).
MISTRUTHmistruth n. Untruth; falsehood.
mistruth n. A statement which, while technically true, is dishonestly misleading. (Can we add an example for this sense?)
MISTRUTH n. a lie.
MISTUTORmistutor v. (Transitive) To tutor badly or amiss.
MISTUTOR v. to instruct badly.
SMUTTIERsmuttier adj. Comparative form of smutty: more smutty.
SMUTTY adj. sexually suggestive.
STRIATUMstriatum n. (Anatomy) The caudate nucleus and the lentiform nucleus considered as a single structure.
STRIATUM n. (Latin) part of the forebrain.
TRITIUMStritiums n. Plural of tritium.
TRITIUM n. an isotope of hydrogen.
TUTORISMtutorism n. (Archaic) tutorship.
TUTORISM n. the act of tutoring.
YTTRIUMSyttriums n. Plural of yttrium.
YTTRIUM n. (Swedish) a rare earth element.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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