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There are 6 eight-letter words containing 2I, N, 2S, T and U

SINUITISsinuitis n. Alternative form of sinusitis.
SINUITIS n. inflammation of a sinus, also SINUSITIS.
SIRTUINSsirtuins n. Plural of sirtuin.
SIRTUIN n. any of a group of enzymes which regulate cell metabolism and aging.
SKINSUITskinsuit n. A skintight suit.
SKINSUIT n. a one-piece skintight garment worn by cyclists, athletes, etc.
SUITINGSsuitings n. Plural of suiting.
SUITING n. fabric for making suits.
TISSUINGtissuing v. Present participle of tissue.
TISSUE v. to weave into a fine, sheer fabric.
UNITISESunitises v. Third-person singular simple present indicative form of unitise.
UNITISE v. to divide into units, also UNITIZE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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