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There are 4 eight-letter words containing 2I, N, 2O, S and T

COITIONScoitions n. Plural of coition.
COITION n. sexual intercourse, also COITUS.
INOSITOLinositol n. (Biochemistry) A simple sugar alcohol (hexahydroxycyclohexane, chemical formula: C6H12O6) which occurs…
INOSITOL n. an alcohol found in plant and animal tissue, also INOSITE.
ISOTONICisotonic adj. (Of two solutions) Having the same osmotic pressure.
isotonic adj. (Of a medical solution) Having the same concentration of solutes as human blood.
isotonic adj. (Of two muscles) Having equal tension.
POSITIONposition n. A place or location.
position n. A post of employment; a job.
position n. A status or rank.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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