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There are 15 fifteen-letter words containing 2I, M, O, S and 2U

CIRCUMAMBAGIOUScircumambagious adj. Of or relating to circumambages; circumlocutionary.
CIRCUMAMBAGIOUS adj. roundabout in speech.
CIRCUMLOCUTIONScircumlocutions n. Plural of circumlocution.
CIRCUMLOCUTION n. an overly complicated means of expression.
CIRCUMNUTATIONScircumnutations n. Plural of circumnutation.
CIRCUMNUTATION n. rotation in a nodding position, as the helical path described by the growing point of a plant.
CIRCUMVOLUTIONScircumvolutions n. Plural of circumvolution.
CIRCUMVOLUTION n. anything winding or sinuous.
DEMUTUALISATIONdemutualisation n. Alternative spelling of demutualization.
DEMUTUALISATION n. the process of demutualising, also DEMUTUALIZATION.
IMMUNODIFFUSIONimmunodiffusion n. A technique used to detect the reaction between an antigen and an antibody by observing the behavior…
IMMUNODIFFUSION n. any of various analytical techniques that involve antigen and antibody solutions diffusing toward each other in a gel until antibody binds specifically to antigen to form a precipitate.
IMMUNOGLOBULINSimmunoglobulins n. Plural of immunoglobulin.
IMMUNOGLOBULIN n. an immune protein.
IMMUNOSTIMULANTimmunostimulant n. (Immunology, pharmacology) Any substance that stimulates an immune response.
immunostimulant adj. (Immunology, pharmacology) That stimulates an immune response.
IMMUNOSTIMULANT n. a drug or nutrient which stimulates the body's immune system.
IMPECUNIOUSNESSimpecuniousness n. The property of being impecunious.
IMPECUNIOUS n. without money; penniless.
MISPUNCTUATIONSmispunctuations n. Plural of mispunctuation.
MISPUNCTUATION n. a wrong punctuation.
MULTITUDINOUSLYmultitudinously adv. In a multitudinous way.
MULTITUDINOUS adv. existing in a great multitude.
NONEQUILIBRIUMSnonequilibriums n. Plural of nonequilibrium.
NONEQUILIBRIUM n. lack of equilibrium.
PUSILLANIMOUSLYpusillanimously adv. In a pusillanimous manner.
PUSILLANIMOUS adv. lacking courage, timid.
ULTIMOGENITURESultimogenitures n. Plural of ultimogeniture.
ULTIMOGENITURE n. inheritance by the youngest child.
UNCIRCUMCISIONSuncircumcisions n. Plural of uncircumcision.
UNCIRCUMCISION n. the state of not being circumcised.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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