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There are 3 twelve-letter words containing 3I, P, 2R and U

ANTIPRURITICantipruritic n. (Pharmacology, dermatology) a medical agent that stops itching.
ANTIPRURITIC adj. alleviating itching.
ANTIPRURITIC n. a drug used to relieve itching.
PERINEURITICPERINEURITIC adj. relating to perineuritis, inflammation of the perineurium.
PERINEURITISperineuritis n. (Medicine) Inflammation of the perineurium.
PERINEURITIS n. inflammation of the perineurium.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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