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There are 20 ten-letter words containing 2I, M, O, R, S and U

FORTUITISMfortuitism n. The doctrine that chance is involved in natural events rather than absolute determinism.
FORTUITISM n. belief in evolution by chance variation.
FUMITORIESfumitories n. Plural of fumitory.
FUMITORY n. a plant once used to treat scurvy, also FEMETARY, FEMITER, FENITAR.
HUMORISTIChumoristic adj. Pertaining to a humorist or his or her style.
HUMORISTIC adj. of, pertaining to, or resembling, a humorist.
IMINOUREASIMINOUREA n. a strongly basic compound used in organic synthesis, aka guanidine.
IMMERITOUSimmeritous adj. (Obsolete) undeserving.
IMMERITOUS adj. (archaic) undeserving.
IMPERVIOUSimpervious adj. Unaffected or unable to be affected by something.
impervious adj. Preventive of any penetration; impenetrable, impermeable, particularly of water.
impervious adj. Immune to damage or effect.
IRIDOSMIUMiridosmium n. Iridosmine.
IRIDOSMIUM n. a very hard corrosion-resistant white or grey natural alloy of osmium and iridium used esp. in pen nibs, also IRIDOSMINE, OSMIRIDIUM.
LIMIVOROUSlimivorous adj. Eating mud or soil for organic matter in it.
LIMIVOROUS adj. feeding on mud.
MIGRAINOUSmigrainous adj. Of, relating to, or afflicted with migraine.
MIGRAINOUS adj. of or like a migraine.
MINICOURSEminicourse n. A brief educational course.
MINICOURSE n. a short course.
MISROUTINGmisrouting v. Present participle of misroute.
misrouting n. An incorrect routing.
MISROUTE v. to route incorrectly.
MOISTURISEmoisturise v. Alternative spelling of moisturize.
MOISTURISE v. to add moisture to, also MOISTURIZE.
MOISTURIZEmoisturize v. (Transitive) To make more moist.
moisturize v. (Transitive) To make more humid.
MOISTURIZE v. to add moisture to, also MOISTURISE.
OSMIRIDIUMosmiridium n. (Mineralogy) A hard, corrosion-resistant alloy of osmium and iridium, used in pen nibs.
OSMIRIDIUM n. a very hard corrosion-resistant white or grey natural alloy of osmium and iridium, also IRIDOSMINE, IRIDOSMIUM.
REUNIONISMreunionism n. A policy in favour of reunion.
REUNIONISM n. a policy of reunification.
ROUTINISMSroutinisms n. Plural of routinism.
ROUTINISM n. the practice of doing things with undiscriminating, mechanical regularity.
SANITORIUMsanitorium n. Alternative spelling of sanatorium.
SANITORIUM n. a hospital, esp. for tuberculosis, also SANATORIUM, SANITARIUM.
TRIFOLIUMStrifoliums n. Plural of trifolium.
TRIFOLIUM n. (Latin) any leguminous plant of the large genus Trifolium, characterized by trifoliate leaves.
TUTIORISMSTUTIORISM n. the doctrine that one should take the safer moral course.
ZIRCONIUMSzirconiums n. Plural of zirconium.
ZIRCONIUM n. a rare element of the carbon-silicon group.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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