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There are 15 ten-letter words containing 2I, 2L, O and 2S

CALLIOPSIScalliopsis n. A flower of the genus Coreopsis.
Calliopsis prop.n. (Archaic) A taxonomic genus within the family Asteraceae – now Coreopsis sect. Calliopsis.
Calliopsis prop.n. A taxonomic genus within the family Andrenidae – certain andrenid bees.
COLLINSIAScollinsias n. Plural of collinsia.
COLLINSIA n. a North American plant of the scrophulariaceous genus Collinsia, having blue, white, or purple flowers.
COLLISIONScollisions n. Plural of collision.
COLLISION n. the state of being struck together.
ELLIPSOIDSellipsoids n. Plural of ellipsoid.
ELLIPSOID n. a solid, all plane sections of which are ellipses or circles.
ISOCLINALSisoclinals n. Plural of isoclinal.
ISOCLINAL n. a line connecting points of same magnetic dip, also ISOCLINIC.
PILLORISESpillorises v. Third-person singular simple present indicative form of pillorise.
PILLORISE v. to pillory, also PILLORIZE.
POLLINISESPOLLINISE v. to pollinate, also POLLINIZE.
POLLINOSISpollinosis n. An allergy to grass and other pollen which causes cold symptoms in sufferers; hay fever.
POLLINOSIS n. an allergic reaction to pollen; hay-fever, also POLLENOSIS.
SIALOLITHSsialoliths n. Plural of sialolith.
SIALOLITH n. a calculus in a salivary gland.
SILICULOSEsiliculose adj. (Botany) Bearing silicles.
siliculose adj. (Botany) Relating to, or resembling, silicles.
siliculose adj. (Obsolete) Full of, or consisting of, husks; husky.
SILKOLINESsilkolines n. Plural of silkoline.
SILKOLINE n. a soft light cotton fabric resembling silk, also SILKALENE, SILKALINE.
SOLSTITIALsolstitial adj. Pertaining to a solstice.
solstitial adj. Occurring on a solstice.
SOLSTITIAL adj. of or pertaining to a solstice.
SOLUBILISEsolubilise v. Alternative spelling of solubilize.
SOLUBILISE v. to render soluble, also SOLUBILIZE.
SPADILLIOSSPADILLIO n. (obsolete) the ace of spades in the game of ombre, also SPADILLE, SPADILLO.
SQUILLIONSsquillions n. Plural of squillion.
SQUILLION n. an indefinitely large number.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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