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There are 4 ten-letter words containing 3I, 2R and 2T

IRRITATINGirritating adj. Causing irritation, annoyance or pain.
irritating adj. Stimulating or exciting a response.
irritating v. Present participle of irritate.
IRRITATIONirritation n. The act of irritating or annoying.
irritation n. The state of being irritated.
irritation n. A things or person that annoys.
IRRITATIVEirritative adj. Serving to excite or irritate.
irritative adj. Accompanied with, or produced by, increased action or irritation.
irritative n. Any substance causing irritation; an irritant.
TRINITRINSTRINITRIN n. glyceryl trinitrate, used to treat angina pectoris.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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