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There are 17 words containing 2I, S, U, X and Y

EXIMIOUSLYeximiously adv. In an eximious way; with distinction, outstandingly.
EXIMIOUS adv. (archaic) choice, excellent.
OXYURIASISoxyuriasis n. Pinworm infection; enterobiasis.
OXYURIASIS n. pinworm infestation.
BISEXUALITYbisexuality n. (Of humans or other animals) The state of being sexually or romantically attracted to members of either sex or gender.
bisexuality n. (Chiefly botany) The state of being bisexual (“having both male and female parts or roles”).
BISEXUALITY n. the state of being bisexual.
EXCLUSIVITYexclusivity n. The quality of being exclusive.
EXCLUSIVITY n. the state of being exclusive.
EXQUISITELYexquisitely adv. In an exquisite manner.
exquisitely adv. Exceedingly; in the highest degree.
EXQUISITE adv. delicate and intricate.
INNOXIOUSLYinnoxiously adv. (Archaic) In an innoxious manner.
INNOXIOUS adv. harmless.
EXHAUSTIVITYexhaustivity n. The condition of being exhaustive.
EXHAUSTIVITY n. the state of being exhaustive.
EXSANGUINITYexsanguinity n. (Medicine) Lack of blood.
EXSANGUINITY n. the state of being exsanguine, without blood.
UNISEXUALITYunisexuality n. The property of being unisexual (having characteristics of a single sex); (especially in botany) the…
unisexuality n. The state of being unisex (suitable for any sex).
UNISEXUALITY n. the state of being unisexual.
AMBISEXUALITYambisexuality n. (Uncountable) The state of being ambisexual.
ambisexuality n. (Countable) An instance of ambisexual behaviour.
AMBISEXUALITY n. the state of being an ambisexual.
ANTISEXUALITYantisexuality n. Opposition to sexuality.
ANTISEXUALITY n. being antisexual.
EXPEDITIOUSLYexpeditiously adv. In an expeditious manner.
EXPEDITIOUS adv. characterized by or acting promptly and efficiently.
INEXHAUSTIBLYinexhaustibly adv. In an inexhaustible manner.
inexhaustibly adv. To an inexhaustible degree.
INEXHAUSTIBLE adv. not exhaustible.
OMNISEXUALITYomnisexuality n. Pansexuality.
EXHAUSTIBILITYexhaustibility n. The property of being exhaustible.
EXHAUSTIBILITY n. the state of being exhaustible.
INEXCUSABILITYinexcusability n. The quality of being inexcusable.
INEXCUSABILITY n. the quality of being inexcusable.
INTERSEXUALITYintersexuality n. The state of having the physical features of both sexes, or of having ambiguous sex, i.e. not unambiguously…
INTERSEXUALITY n. the state of being intersexual.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 203 words
  • Scrabble in French: 7 words
  • Scrabble in Spanish: 8 words
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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