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There are 17 eight-letter words containing 2I, P, S and 2T

OPTICISTopticist n. One who studies optics.
OPTICIST n. one engaged in the study of light and vision.
OPTIMISToptimist n. A person who expects a favourable outcome.
optimist n. A believer in optimism.
Optimist n. (Nautical) A small centre-board sailing dinghy designed to train and introduce young children into sailing.
PETITIOSPETITIO n. a short form of petitio principii, a form of fallacious reasoning in which the conclusion has been assumed in the premises; begging the question.
PIETISTSpietists n. Plural of pietist.
Pietists n. Plural of Pietist.
PIETIST n. a person characterized by or professing (often affected or exaggerated) piety.
PITHIESTpithiest adj. Superlative form of pithy: most pithy.
PITHY adj. full of pith, to the point.
PITTINGSpittings n. Plural of pitting.
PITTING n. an arrangement of cavities or depressions.
PITTITESpittites n. Plural of pittite.
Pittites n. Plural of Pittite.
PITTITE n. (obsolete) someone who frequents the pit of a theatre.
PITUITASPITUITA n. (archaic) phlegm, mucus, also PITUITE.
PITUITESPITUITE n. (archaic) phlegm, mucus, also PITUITA.
RISPETTIrispetti n. Plural of rispetto.
RISPETTO n. (Italian) a type of Italian folksong with 8-line stanzas.
SPITTIERSPITTY adj. marked with saliva.
SPITTINGspitting v. Present participle of spit.
spitting n. (Chiefly archaic, medicine) expectoration.
spitting n. (Uncountable) An appearance on the surface of melted silver or platinum allowed to cool slowly, jets…
STIPITESstipites n. Plural of stipes.
STIPES n. (Latin) a slender supporting part of a plant, also STIPE.
TIDYTIPStidytips n. Any of the flowering plants of the genus Layia in the daisy family; they are erect annual herbs with…
TIDYTIPS n. a California composite plant, the flower of which has yellow rays tipped with white.
TIPPIESTtippiest adj. Superlative form of tippy: most tippy.
TIPPY adj. (slang) in the height of fashion.
TIPSIESTtipsiest adj. Superlative form of tipsy: most tipsy.
TIPSY adj. slightly drunk.
TRIPIESTTRIPY adj. like tripe, worthless, also TRIPEY.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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