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There are 11 eight-letter words containing 2I, M and 3S

MIOSISESMIOSIS n. (Greek) excessive contraction of the pupil of the eye, also MYOSIS.
MISSIESTMISSY adj. like a miss.
MISSILESmissiles n. Plural of missile.
MISSILE n. an object or weapon that is thrown or projected.
MISSIONSmissions n. Plural of mission.
missions v. Third-person singular simple present indicative form of mission.
MISSION v. to send to perform a specific task.
MISSISESmissises n. Plural of missis.
MISSIS n. (colloquial) wife, also MISSUS.
MISSIVESmissives n. Plural of missive.
MISSIVE n. a written communication.
MISSUITSmissuits v. Third-person singular simple present indicative form of missuit.
MISSUIT v. to suit badly.
SASHIMISsashimis n. Plural of sashimi.
SASHIMI n. (Japanese) fish, sliced paper-thin and served raw.
SEISMISMseismism n. Seismic activity.
SEISMISM n. the natural activity involved in earthquakes.
SEMIOSISsemiosis n. (Semiotics) Any activity, conduct, or process that involves signs, including the production of meaning.
SEMIOSIS n. (Greek) a process in which something functions at organism.
SIZEISMSSIZEISM n. prejudice against people on account of their size, also SIZISM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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