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There is only one fifteen-letter word containing I, 2M, S, U and Z

ISOIMMUNIZATIONisoimmunization n. The development of antibodies in response to an isoantigen.
ISOIMMUNIZATION n. the development of antibodies within an individual against antigens from another individual of the same species, also ISOIMMUNISATION.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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