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There are 20 twelve-letter words containing 2I, M, O, S and X

AMOXICILLINSamoxicillins n. Plural of amoxicillin.
AMOXICILLIN n. an antibiotic drug, a type of semisynthetic penicillin, also AMOXYCILLIN.
AMOXYCILLINSamoxycillins n. Plural of amoxycillin.
AMOXYCILLIN n. an antibiotic drug, a type of semisynthetic penicillin, also AMOXICILLIN.
AXINOMANCIESAXINOMANCY n. divination using an axe or hatchet.
AXIOMATISINGaxiomatising v. Present participle of axiomatise.
AXIOMATISE v. to make axiomatic, also AXIOMATIZE.
COMPLEXIFIEScomplexifies v. Third-person singular simple present indicative form of complexify.
COMPLEXIFY v. to render complex.
COMPLEXITIEScomplexities n. Plural of complexity.
COMPLEXITY n. the state of being complex.
DOMINATRIXESdominatrixes n. Plural of dominatrix.
DOMINATRIX n. a prostitute catering for masochists.
EXAMINATIONSexaminations n. Plural of examination.
EXAMINATION n. the act of examining.
EXANIMATIONSEXANIMATION n. lifelessness.
EXCLUSIONISMexclusionism n. The quality of being exclusionist.
exclusionism n. A policy or ideology that favors exclusion of some individuals or groups from a nation, sect, etc.
EXCLUSIONISM n. the practice of excluding others from some right or privilege.
EXOTERICISMSEXOTERICISM n. the state of being exoteric.
EXPANSIONISMexpansionism n. The policy, of a nation, of expanding its territory or its economic influence.
EXPANSIONISM n. a policy or practice of expansion and esp. of territorial expansion by a nation.
EXPROMISSIONexpromission n. (Law) The intervention of a new debtor, substituted for the former one, who is consequently discharged…
EXPROMISSION n. relieving another person's debt by taking it upon oneself.
IMMUNOTOXINSimmunotoxins n. Plural of immunotoxin.
IMMUNOTOXIN n. a toxin with immunosuppressive effects.
INTOXIMETERSintoximeters n. Plural of intoximeter.
INTOXIMETER n. a device for measuring the amount of alcohol in the blood of a person who breathes into it, and showing this measurement on a printout.
MAXIMISATIONmaximisation n. Alternative spelling of maximization.
MAXIMISATION n. the act of maximising, also MAXIMATION, MAXIMIZATION.
MOXIBUSTIONSmoxibustions n. Plural of moxibustion.
MOXIBUSTION n. cauterization by use of moxa.
OXIDIMETRIESOXIDIMETRY n. a branch of volumetric analysis in which oxidizing agents are used in titrations.
PROXIMATIONSproximations n. Plural of proximation.
PROXIMATION n. immediate nearness in time, place, relationship, etc., also PROXIMITY.
TOXICOMANIAStoxicomanias n. Plural of toxicomania.
TOXICOMANIA n. a morbid craving for poisons.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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