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There are 8 ten-letter words containing 2I, 2N, O and X

ANTITOXINSantitoxins n. Plural of antitoxin.
ANTITOXIN n. an antidote to a toxin.
EXTINCTIONextinction n. The action of making or becoming extinct; annihilation.
extinction n. (Astronomy) The absorption or scattering of electromagnetic radiation emitted by astronomical objects…
extinction n. (Pathology) The inability to perceive multiple stimuli simultaneously.
INDEXATIONindexation n. The adjustment of an economic variable (such as a salary) according to an index (such as that of inflation).
INDEXATION n. a system by which wages, rates of interest etc. are directly linked to changes in the cost of living index.
INFIXATIONinfixation n. (Linguistic morphology) Word-formation involving an infix or infixes; adding an infix to a word.
infixation n. (Grammar) The state or quality of being infixed.
INFIXATION n. the act of infixing.
INFLEXIONSinflexions n. Plural of inflexion.
INFLEXION n. a change in the form of a word, usually modification or affixation, signalling change in such grammatical functions as tense, voice, mood, person, also INFLECTION.
INFLUXIONSinfluxions n. Plural of influxion.
INFLUXION n. a flowing in, also INFLUX.
INTOXICANTintoxicant n. Something which intoxicates; an intoxicating agent.
intoxicant n. Poison.
intoxicant adj. Intoxicating.
OUTJINXINGOUTJINX v. to surpass in jinxing.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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