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There are 8 ten-letter words containing 3I, 2O and S

BIOPOIESISbiopoiesis n. (Biology) abiogenesis.
BIOPOIESIS n. the creation of living from nonliving material as an evolutionary process.
IDIOTICONSidioticons n. Plural of idioticon.
IDIOTICON n. a dialect dictionary.
IMPOSITIONimposition n. The act of imposing, laying on, affixing, enjoining, inflicting, obtruding, and the like.
imposition n. An unwelcome burden, presence, or obligation.
imposition n. That which is imposed, levied, or enjoined.
IODISATIONiodisation n. Alternative spelling of iodization.
IODISATION n. the act of iodising, also IODIZATION.
IONISATIONionisation n. Alternative spelling of ionization.
IONISATION n. the act of ionising, also IONIZATION.
LIPOIDOSISlipoidosis n. The presence of anisotropic lipoids in the cells.
OPINIONISTopinionist n. One fond of his own notions, or unduly attached to his own opinions.
opinionist n. One whose unusual or heretical belief or opinion contrasts with the dominant view.
OPINIONIST n. one fond of his own notions, or unduly attached to his own opinions.
OTIOSITIESotiosities n. Plural of otiosity.
OTIOSITY n. the state of being otiose.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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