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There are 19 eight-letter words containing I, R, S, T and X

DEXTRINSdextrins n. Plural of dextrin.
DEXTRIN n. a substance used as an adhesive, also DEXTRINE.
DRUXIESTDRUXY adj. of timber, having hidden decayed spots, also DRICKSIE.
EXCITERSexciters n. Plural of exciter.
EXCITER n. one that excites, also EXCITOR.
EXCITORSexcitors n. Plural of excitor.
EXCITOR n. one that excites, also EXCITER.
EXORCISTexorcist n. A person, especially a priest, who practices exorcism.
EXORCIST n. one who practices exorcism.
EXTRAITSEXTRAIT n. (French) an extract.
FIXTURESfixtures n. Plural of fixture.
FIXTURE n. a permanent part of a house.
INTERSEXintersex adj. (Of an individual) Having any of a variety of inherent conditions (in a species with distinct sexes)…
intersex adj. (Fantasy) A person who can get pregnant and also impregnate someone else.
intersex n. The condition of being intersex; intersexuality.
LUXURISTluxurist n. (Obsolete) One given to luxury.
LUXURIST n. someone given to luxury.
MATRIXESmatrixes n. Plural of matrix.
MATRIX n. (Latin) the womb; that in which anything is embedded, also MATRICE.
MIXTURESmixtures n. Plural of mixture.
MIXTURE n. the product of mixing.
NITROXESNITROX n. a mixture of nitrogen and oxygen, used in underwater breathing apparatus.
PREEXISTpreexist v. To exist before something else.
preëxist v. Rare spelling of preexist.
pre-exist v. Alternative spelling of preexist.
SEXTARIIsextarii n. Plural of sextarius.
SEXTARIUS n. (Latin) an ancient Roman unit of liquid measure.
TRANSFIXtransfix v. (Transitive) To render motionless, by arousing terror, amazement or awe.
transfix v. (Transitive) To pierce with a sharp pointed weapon.
transfix v. (Transitive) To fix or impale.
TRIAXONStriaxons n. Plural of triaxon.
TRIAXON n. a sponge spicule with three axes, also TRIAXIAL.
TRIMIXESTRIMIX n. a mixture of nitrogen, helium and oxygen, used by deep-sea divers.
TRIOXIDStrioxids n. Plural of trioxid.
TRIOXID n. an oxide containing three atoms of oxygen; as, sulphur trioxide, also TRIOXIDE.
TUTRIXEStutrixes n. Plural of tutrix.
TUTRIX n. (obsolete) a female tutor, also TUTORESS, TUTRESS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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