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There are 8 eight-letter words containing 2I, P, T and Z

EPIZOITEepizoite n. Any epizoic organism.
EPIZOITE n. an epizoic organism.
OPTIMIZEoptimize v. (Originally intransitive) To act optimistically or as an optimist.
optimize v. (Transitive) To make (something) optimal.
optimize v. (Transitive) To make (something) more efficient, such as a computer program.
PATINIZEpatinize v. (Transitive) To give a patina to.
PATINIZE v. to give a patina to, also PATINATE, PATINISE.
PINTSIZEpintsize adj. Alternative form of pint-size.
pint-size adj. Synonym of pint-sized.
PINTSIZE adj. very small, also PINTSIZED.
PYRITIZEpyritize v. (Transitive) To convert something into pyrites.
PYRITIZE v. to convert into pyrites, also PYRITISE.
SPRITZIGspritzig adj. Of wine: lightly sparkling.
SPRITZIG n. (German) a usually sparkling white wine.
TRAPEZIItrapezii n. Plural of trapezius.
TRAPEZIUS n. (Latin) either of two, flat large muscles running from the base of the occiput to the middle of the back.
ZIPPIESTzippiest adj. Superlative form of zippy: most zippy.
ZIPPY adj. full of zip, energy.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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