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There are 17 eight-letter words containing 2I, N, Q and S

EQUINIASEQUINIA n. glanders, a contagious horse disease.
INQILABSinqilabs n. Plural of inqilab.
INQILAB n. (Urdu) in India, Pakistan etc., a revolution.
INQUIETSinquiets v. Third-person singular simple present indicative form of inquiet.
INQUIET v. to disturb.
INQUIRESinquires v. Third-person singular simple present indicative form of inquire.
INQUIRE v. to ask about, also ENQUIRE.
QUIBLINSQUIBLIN n. (obsolete) a quibble, also QUILLET.
QUININASQUININA n. a colourless, bitter alkaloid obtained from cinchona bark, used as an antipyretic or analgesic, also QUININ, QUININE.
QUININESquinines n. Plural of quinine.
quinines v. Third-person singular simple present indicative form of quinine.
QUININE n. a colourless, bitter alkaloid obtained from cinchona bark, used as an antipyretic or analgesic, also QUININ, QUININA.
QUINOIDSquinoids n. Plural of quinoid.
QUINOID n. a quinonoid substance.
QUINSIEDquinsied adj. Afflicted with quinsy.
QUINSIED adj. suffering from quinsy, severe inflammation of tonsils and throat.
QUINSIESquinsies n. Plural of quinsy.
QUINSY n. severe inflammation of tonsils and throat.
QUINTICSquintics n. Plural of quintic.
QUINTIC n. an equation of the fifth degree.
QUINTINSquintins n. Plural of quintin.
Quintins prop.n. Plural of Quintin.
QUINTIN n. a kind of fine linen.
QUINZIESquinzies n. Plural of quinzy.
QUINZIE n. (Inuit) a shelter made by hollowing out a pile of snow, also QUINZHEE.
QUISLINGquisling n. (Derogatory) A traitor who collaborates with the enemy.
quisling v. Present participle of quisle.
Quisling n. Alternative letter-case form of quisling.
SQUINIEDsquinied v. Simple past tense and past participle of squiny.
SQUINY v. (dialect) to squint, also SQUINNY.
SQUINIESsquinies v. Third-person singular simple present indicative form of squiny.
SQUINY v. (dialect) to squint, also SQUINNY.
SQUIRINGsquiring v. Present participle of squire.
SQUIRE v. to escort.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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