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List of 6-letter words containing

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There are 13 six-letter words containing I, O, P and 2S

DIPSOSdipsos n. Plural of dipso.
DIPSO n. (short for) a dipsomaniac, one addicted to drink.
GOSSIPgossip n. (Countable) Someone who likes to talk about other people’s private or personal business.
gossip n. (Uncountable) Idle talk about someone’s private or personal matters, especially someone not present.
gossip n. (Uncountable) Idle conversation in general.
INSPOSINSPO n. someone or something that is a source of inspiration.
OPSINSopsins n. Plural of opsin.
OPSIN n. a protein which forms part of the visual pigment rhodopsin.
PISCOSpiscos n. Plural of pisco.
PISCO n. a Peruvian brandy.
POISESpoises v. Third-person singular simple present indicative form of poise.
poises n. Plural of poise.
POISE v. to hold in a state of equilibrium.
POSIESposies n. Plural of posy.
POSY n. a small bunch of flowers.
POSITSposits n. Plural of posit.
posits v. Third-person singular simple present indicative form of posit.
POSIT v. to place.
POSSIEpossie n. (Australia, New Zealand, military slang, Digger slang) A firing position.
possie n. (Australia, New Zealand, colloquial) A position or place, especially one that is advantageous.
POSSIE n. (Australian slang) a position, also POZZY.
PSIONSpsions n. Plural of psion.
PSION n. a particle formed by collision of a positron and an electron.
PTOSISptosis n. (Medicine) The prolapse of a bodily organ, especially drooping of the eyelid or the breasts.
PTOSIS n. (Greek) a drooping of the upper eyelid.
PYOSISpyosis n. (Medicine) formation of pus.
PYOSIS n. the formation of pus.
SPOILSspoils n. That which is taken from another by violence; especially, the plunder taken from an enemy; pillage; booty.
spoils n. Waste material left over in the course of excavation, construction, mining, or dredging operations.
spoils n. Public offices and their benefits regarded as the peculiar property of a successful party or faction…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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