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There are 14 fourteen-letter words containing 2I, S and 2Y

AMITRYPTYLINESAMITRYPTYLINE n. an antidepressant drug, also AMITRIPTYLINE.
ANTIPSYCHIATRYantipsychiatry adj. Opposed to psychiatry.
antipsychiatry n. A form of psychoanalysis based on existentialist and sociological concepts.
ANTIPSYCHIATRY adj. opposed to psychiatry.
DISYLLABIFYINGdisyllabifying v. Present participle of disyllabify.
DISYLLABIFY v. to make into two syllables.
GLYCOSIDICALLYglycosidically adv. In a glycosidic manner; by means of a glycoside.
GLYCOSIDIC adv. of or like a glycoside.
HISTOLYTICALLYhistolytically adv. By means of, or in terms of, histolysis.
HISTOLYTIC adv. of or pertaining to histolysis, or the degeneration of tissues.
HYGROSCOPICITYhygroscopicity n. (Uncountable) The state of being hygroscopic.
hygroscopicity n. (Countable) The degree to which a substance is hygroscopic.
HYGROSCOPICITY n. the state of being hygroscopic.
HYPERINTENSITYhyperintensity n. An area of high intensity (for example, as seen in magnetic resonance imaging).
HYPERVISCOSITYhyperviscosity n. Increased viscosity, especially of the blood.
HYPERVISCOSITY n. extreme viscosity.
HYPOTHYROIDISMhypothyroidism n. (Pathology) The disease state caused by insufficient production of thyroid hormone by the thyroid gland.
HYPOTHYROIDISM n. deficient activity of the thyroid gland.
POLYDISPERSITYpolydispersity n. (Uncountable) The state of being polydisperse.
polydispersity n. (Countable) A measure of the degree to which a colloid is polydisperse.
POLYDISPERSITY n. the state of being polydisperse, characterized by particles of varied sizes in the dispersed phase of a disperse system.
POLYMYOSITISESPOLYMYOSITIS n. inflammation of several muscles at the same time.
SYMBIONTICALLYSYMBIONTIC adv. of or like a symbiont.
SYPHILITICALLYsyphilitically adv. (Medicine) In a syphilitic manner; with venereal disease.
SYPHILITIC adv. of or like syphilis, a venereal disease.
SYRINGOMYELIASsyringomyelias n. Plural of syringomyelia.
SYRINGOMYELIA n. a chronic progressive disease of the spinal cord associated with sensory disturbances, muscle atrophy, and spasticity.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 119 words
  • Scrabble in French: 3 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: no word
  • Scrabble in German: no word
  • Scrabble in Romanian: no word


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