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There are 12 twelve-letter words containing 2I, Q and 2R

EQUILIBRATORequilibrator n. (Rare) A device that maintains equilibrium or balance, especially a part of a heavy gun (e.g. an artillery…
EQUILIBRATOR n. one who equilibrates.
PERQUISITORSperquisitors n. Plural of perquisitor.
PERQUISITOR n. the first purchaser of an estate.
PREREQUIRINGprerequiring v. Present participle of prerequire.
PREREQUIRE v. to require beforehand.
PREREQUISITEprerequisite adj. Required as a prior condition of something else; necessary or indispensable.
prerequisite n. Something that is required as necessary or indispensable, or as a prior condition of something else.
prerequisite n. In education, a course or topic that must be completed before another course or topic can be started…
RELINQUISHERrelinquisher n. One who relinquishes.
RELINQUISHER n. one who relinquishes.
SQUIRARCHIESsquirarchies n. Plural of squirarchy.
SQUIRARCHY n. squires collectively, also SQUIRAGE, SQUIRALITY, SQUIRALTY, SQUIREAGE, SQUIREARCHY.
SQUIRRELFISHsquirrelfish n. Any member of the subfamily Holocentrinae of the family Holocentridae of ray-finned fish.
SQUIRRELFISH n. any of various brightly-coloured marine fishes of the family Holocentridae of shallow tropical waters, so called because their large eyes resemble those of the squirrel.
SQUIRRELIESTSQUIRRELY adj. like a squirrel, also SQUIRRELLY.
SQUIRRELLIERsquirrellier adj. Comparative form of squirrelly: more squirrelly.
SQUIRRELLY adj. like a squirrel, also SQUIRRELY.
SQUIRRELLINGsquirrelling v. Present participle of squirrel.
squirrelling n. Storing up, hoarding.
squirrelling n. (Obsolete) The sport of hunting squirrels.
TRANQUILISERtranquiliser n. (Britain, uncommon) Alternative spelling of tranquilizer.
TRANQUILISER n. a drug that has a tranquillising effect, also TRANQUILIZER, TRANQUILLISER, TRANQUILLIZER.
TRANQUILIZERtranquilizer n. That which tranquillizes or soothes.
tranquilizer n. (Pharmacology) A drug used to reduce anxiety or tension.
TRANQUILIZER n. a drug that has a tranquillising effect, also TRANQUILISER, TRANQUILLISER, TRANQUILLIZER.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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