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There are 13 ten-letter words containing I, 2M, S and X

AMPHIMIXESamphimixes n. Plural of amphimixis.
AMPHIMIXIS n. interbreeding; intermixing of two individuals' genetic matter.
AMPHIMIXISamphimixis n. (Uncountable) sexual reproduction.
amphimixis n. (Countable) The union of a male and female gamete.
AMPHIMIXIS n. interbreeding; intermixing of two individuals' genetic matter.
EXCAMBIUMSEXCAMBIUM n. in Scots law, exchange of lands, also EXCAMBION.
EXTREMISMSextremisms n. Plural of extremism.
EXTREMISM n. the taking of an extreme position.
HEXAMERISMhexamerism n. Six-part radial symmetry.
HEXAMERISM n. the state of being hexamerous.
IMMIXTURESimmixtures n. Plural of immixture.
IMMIXTURE n. freedom from mixture; purity.
MAXIMALISTmaximalist adj. (Art, music, literature) Preferring redundancy; tending to do or provide more rather than less.
maximalist adj. (Politics, diplomacy) Aggressive, expansive.
maximalist adj. (Religion) Relating to religious or Biblical maximalism.
MAXIMISERSmaximisers n. Plural of maximiser.
MAXIMISER n. one who maximises, also MAXIMIZER.
MAXIMISINGmaximising v. Present participle of maximise.
MAXIMISE v. to make as great as possible, also MAXIMIZE.
MAXIMIZERSmaximizers n. Plural of maximizer.
MAXIMIZER n. one who maximizes, also MAXIMISER.
MELOXICAMSMELOXICAM n. a drug used to treat osteoarthritis and rheumatoid arthritis.
MIXMASTERSmixmasters n. Plural of mixmaster.
MIXMASTER n. a disc jockey.
SUBMAXIMALsubmaximal adj. Less than maximal.
SUBMAXIMAL adj. below maximal.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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