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There are 19 ten-letter words containing 2I, 2S and X

ANTISEXISTantisexist adj. Opposed to sexism.
antisexist n. One who opposes sexism.
ANTISEXIST n. one opposed to sexism.
BISSEXTILEbissextile adj. Having an intercalary day, particularly the quadrennial leap day of the Julian and Gregorian calendars…
bissextile n. Synonym of leap year: a year with an intercalary day.
BISSEXTILE n. the extra day in the leap year.
DEOXIDISESdeoxidises v. Third-person singular simple present indicative form of deoxidise.
DEOXIDISE v. to remove oxygen from, also DEOXIDIZE.
ENDEIXISESENDEIXIS n. (Greek) in medicine, an indication.
EPOXIDISESEPOXIDISE v. to convert into an epoxide, an epoxy compound, also EPOXIDIZE.
EXOTICISESexoticises v. Third-person singular simple present indicative form of exoticise.
EXOTICISE v. to regard or present as exotic, also EXOTICIZE.
EXOTICISMSexoticisms n. Plural of exoticism.
EXOTICISM n. the state of being exotic; also, anything foreign, as a word or idiom.
EXOTICISTSexoticists n. Plural of exoticist.
EXOTICIST n. an enthusiast for the exotic.
EXQUISITESexquisites n. Plural of exquisite.
EXQUISITE n. a person who is obsessively or fashionably exact or fastidious in dress.
MAXIMISERSmaximisers n. Plural of maximiser.
MAXIMISER n. one who maximises, also MAXIMIZER.
OXYURIASISoxyuriasis n. Pinworm infection; enterobiasis.
OXYURIASIS n. pinworm infestation.
PANMIXISESPANMIXIS n. (Greek) random mating within a breeding population, also PANMIXIA.
PIXINESSESPIXINESS n. the state of being playfully mischievous.
QUIXOTISMSquixotisms n. Plural of quixotism.
QUIXOTISM n. quixotic principles, character, or practice; a quixotic action, statement, or idea, also QUIXOTRY.
REOXIDISESreoxidises v. Third-person singular simple present indicative form of reoxidise.
REOXIDISE v. to oxidise again, also REOXIDIZE.
SAXITOXINSsaxitoxins n. Plural of saxitoxin.
SAXITOXIN n. a nerve poison found in molluscs feeding on dinoflagellates of the genus Gonyaulax.
SIXPENNIESsixpennies n. Plural of sixpenny.
SIXPENNY n. a coin worth six pence.
SPINIFEXESspinifexes n. Plural of spinifex.
SPINIFEX n. (Latin) a sharp-pointed Australian grass.
SUFFIXIONSsuffixions n. Plural of suffixion.
SUFFIXION n. the act of suffixing, or the state of being suffixed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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