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There are 15 five-letter words containing I, N, S and U

INCUSincus n. (Anatomy) A small anvil-shaped bone in the middle ear.
incus n. (Meteorology) an accessory cloud, in the shape of an anvil which forms by spreading at the top of a cumulonimbus.
INCUS n. (Latin) an anvil-shaped bone in the middle ear.
INUSTinust adj. (Obsolete) burnt in.
INUST adj. (obsolete) burnt in.
MINUSminus prep. (Mathematics) Made less or reduced by (followed by an expression of number or quantity).
minus prep. (Informal) Without; deprived of.
minus n. (Mathematics) The minus sign (−).
MUNISmunis n. Plural of muni.
MUNI n. a security issued by a government.
NIDUSnidus n. An aggregate of neurons.
nidus n. A nest for insects or small animals.
nidus n. A place of infection in an organism.
NISUSnisus n. A mental or physical effort to attain a specific goal; a striving.
nisus n. The periodic procreative desire manifested in the spring by birds, etc.
nisus n. The contraction of the diaphragm and abdominal muscles to evacuate faeces or urine.
QUINSquins n. Plural of quin.
Quins prop.n. Plural of Quin.
QUIN n. (short for) a quintuplet.
RUINSruins n. Plural of ruin.
ruins v. Third-person singular simple present indicative form of ruin.
RUIN v. to destroy.
SINUSsinus n. (Anatomy, zootomy) A pouch or cavity in a bone or other tissue, especially one in the bones of the face…
sinus n. (Anatomy) An irregular venous or lymphatic cavity, reservoir, or dilated vessel.
sinus n. (Pathology) An abnormal cavity or passage such as a fistula, leading from a deep-seated infection and…
SUINGsuing v. Present participle of sue.
suing n. The act of one who sues for something.
suing n. (Obsolete) The process of soaking through anything.
SUINTsuint n. (Organic chemistry, dated) A substance obtained from the wool of sheep, consisting largely of potash…
SUINT n. a natural grease found in the wool of sheep.
SUNISSunis n. Plural of Suni.
SUNI n. (Bantu) a small South African antelope.
UNAISunais n. Plural of unai.
UNAI n. (Tupi) a two-toed sloth, also UNAU.
UNITSunits n. Plural of unit.
UNIT n. a specific quantity used as a standard of measurement.
USINGusing v. Present participle of use.
using n. Use; utilization.
USE v. to put into service.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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