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There are 20 twelve-letter words containing H, M, 2O and 3S

CHEMIOSMOSESchemiosmoses n. Plural of chemiosmosis.
CHEMIOSMOSIS n. the mechanism by which the synthesis and utilization of the biochemical energy source ATP is regulated.
CHEMIOSMOSISchemiosmosis n. (Chemistry) Any chemical reaction that occurs through an intervening semipermeable membrane, especially…
CHEMIOSMOSIS n. the mechanism by which the synthesis and utilization of the biochemical energy source ATP is regulated.
COSMOSPHEREScosmospheres n. Plural of cosmosphere.
COSMOSPHERE n. an apparatus for showing the position of the earth at any given time with reference to the fixed stars.
COSMOTHEISMSCOSMOTHEISM n. the belief that identifies God with the cosmos.
CUSTOMHOUSEScustomhouses n. Plural of customhouse.
custom␣houses n. Plural of custom house.
CUSTOMHOUSE n. an office or residence for customs officials, also CUSTOMSHOUSE.
CUSTOMSHOUSEcustomshouse n. Alternative form of custom house.
customs␣house n. Alternative form of custom house.
CUSTOMSHOUSE n. an office or residence for customs officials, also CUSTOMHOUSE.
HOMOEOSTASESHOMOEOSTASIS n. a tendency towards health or stable physical conditions, also HOMEOSTASIS.
HOMOEOSTASIShomoeostasis n. Alternative spelling of homeostasis.
homœostasis n. Obsolete spelling of homeostasis.
HOMOEOSTASIS n. a tendency towards health or stable physical conditions, also HOMEOSTASIS.
HUMOROUSNESShumorousness n. (Uncountable) The state or quality of being humorous.
humorousness n. (Countable) The result or product of being humorous.
HUMOROUSNESS n. the state of being humorous.
ISOCHRONISMSisochronisms n. Plural of isochronism.
ISOCHRONISM n. the property of having the same duration; recurring at equal intervals.
ISOMORPHISMSisomorphisms n. Plural of isomorphism.
ISOMORPHISM n. similarity in shape or structure in unrelated forms.
PHOSPHORISMSPHOSPHORISM n. (obsolete) chronic phosphorus poisoning.
PHOTOSYSTEMSphotosystems n. Plural of photosystem.
PHOTOSYSTEM n. either of two photochemical reaction centers consisting chiefly of photosynthetic pigments complexed with protein and occurring in chloroplasts.
PHYSOSTOMOUSphysostomous adj. (Zoology) Having a duct to the air bladder.
physostomous adj. (Zoology) Relating to the Physostomi.
PHYSOSTOMOUS adj. of fishes, having a duct connecting the air bladder to part of the alimentary canal.
SCHISTOSOMALschistosomal adj. Of or pertaining to the schistosome or to schistosomiasis.
SCHISTOSOMAL adj. of or like a schistosome, a disease-causing blood fluke.
SCHISTOSOMESschistosomes n. Plural of schistosome.
SCHISTOSOME n. a disease-causing blood fluke.
SCHUSSBOOMERschussboomer n. (Skiing) A fast downhill skier.
SCHUSSBOOMER n. a very proficient schusser.
SHOPAHOLISMSSHOPAHOLISM n. an addiction to shopping.
SMOOTHNESSESsmoothnesses n. Plural of smoothness.
SMOOTHNESS n. the state of being smooth.
THEOSOPHISMSTHEOSOPHISM n. theosophical tenets.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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