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There are 4 eight-letter words containing H, 2I, P, R and U

HIPPURIChippuric adj. Of or pertaining to hippuric acid or its derivatives.
HIPPURIC adj. denoting an acid.
OPHIURIDophiurid adj. Alternative form of ophiuroid.
ophiurid n. Alternative form of ophiuroid.
OPHIURID n. a member of the Ophiura genus of brittle-stars or sand-stars, also OPHIURA, OPHIURAN, OPHIUROID.
PICHURIMPICHURIM n. (Tupi) a South American tree of the laurel family.
PUIRTITHPUIRTITH n. (Scots) poverty, also POORTITH.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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