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There are 19 twelve-letter words containing H, 2I, 2O and U

ACIDOPHILOUSacidophilous adj. That thrives in an acidic environment.
ACIDOPHILOUS adj. staining readily with acid stains.
AILOUROPHILEailourophile n. Alternative spelling of ailurophile.
AILOUROPHILE n. a cat-lover, also AILUROPHILE.
AILUROPHOBIAailurophobia n. An irrational fear or hatred of cats or other felines.
AILUROPHOBIA n. fear of cats.
AILUROPHOBICailurophobic adj. Having or relating to a fear or hatred of cats.
AILUROPHOBIC adj. having a morbid fear of cats.
DISHONOURINGdishonouring v. Present participle of dishonour.
DISHONOUR v. to deprive of honour, disgrace, also DISHONOR.
HELIOPHILOUSheliophilous adj. (Botany) That needs, or tolerates, a high level of direct sunlight.
HELIOPHILOUS adj. attracted by sunlight.
HEMODILUTIONhemodilution n. (Pathology) An increase in the fluid content of blood (and thus a diminution of the number of cells).
HEMODILUTION n. decreased concentration of cells and solids in the blood resulting from gain of fluid, also HAEMODILUTION.
HOMOIOUSIANShomoiousians n. Plural of homoiousian.
HOMOIOUSIAN n. one of those, in the 4th century maintained that the Son had a like but not the same essence or substance with the Father.
IDIOTHERMOUSIDIOTHERMOUS adj. warm-blooded.
INHARMONIOUSinharmonious adj. (Music) Not in harmony; discordant.
inharmonious adj. Lacking accord or agreement.
INHARMONIOUS adj. not harmonious.
LEIOTRICHOUSleiotrichous adj. Having smooth hair.
LEIOTRICHOUS adj. straight-haired.
LIMNOPHILOUSlimnophilous adj. Loving or having an affinity towards lakes.
LIMNOPHILOUS adj. living in ponds or marshes.
LITHOPHILOUSlithophilous adj. (Biology) That lives in stony or rocky environments.
LITHOPHILOUS adj. living among stones.
MOSQUITOFISHmosquitofish n. Any of several small fish that feed on mosquitoes, but especially those of the genus Gambusia.
MOSQUITOFISH n. a species of freshwater fish, native to the southeastern US.
NITROPHILOUSnitrophilous adj. (Botany, of a plant) Thriving in a habitat rich in nitrogen.
nitrophilous adj. (Ecology, of a habitat) Rich in nitrogen.
NITROPHILOUS adj. of plants, growing in a place where there is a good supply of nitrogen.
RADIOTHORIUMradiothorium n. (Physics) The radioactive isotope thorium-228.
RADIOTHORIUM n. a radioactive isotope of thorium with the mass number 228.
RHIZOPHILOUSRHIZOPHILOUS adj. growing on roots.
UNLIKELIHOODunlikelihood n. Absence of likelihood; the state of being unlikely or improbable; improbability.
UNLIKELIHOOD n. the state of being unlikely.
VIRTUOSOSHIPvirtuosoship n. The status, pursuits, or occupation of a virtuoso.
VIRTUOSOSHIP n. being a virtuoso.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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