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There are 19 fifteen-letter words containing H, I, S, T and X

CANTHAXANTHINESCANTHAXANTHINE n. a naturally occurring carotenoid used esp. as a color additive for food, also CANTHAXANTHIN.
CHEMOTAXONOMIESchemotaxonomies n. Plural of chemotaxonomy.
CHEMOTAXONOMY n. the classification of plants and animals based on similarities and differences in biochemical composition.
CHEMOTAXONOMISTchemotaxonomist n. One who studies chemotaxonomy.
CHEMOTAXONOMIST n. one who practises chemotaxonomy.
DEXAMPHETAMINESDEXAMPHETAMINE n. the dextrorotatory isomer of amphetamine, used as a stimulant.
EXHIBITIONISTICexhibitionistic adj. Having a tendency toward exhibitionism.
EXHIBITIONISTIC adj. characterised by exhibitionism.
EXOTHERMICITIESexothermicities n. Plural of exothermicity.
EXOTHERMICITY n. the state of being exothermic.
EXTINGUISHMENTSextinguishments n. Plural of extinguishment.
EXTINGUISHMENT n. the act of extinguishing.
HETEROFLEXIBLESheteroflexibles n. Plural of heteroflexible.
HETEROFLEXIBLE n. one of flexible sexual orientation.
HETEROSEXUALITYheterosexuality n. The state of being sexually and romantically attracted primarily or exclusively to persons of the opposite sex.
heterosexuality n. Sexual activity with a person of the opposite sex.
HETEROSEXUALITY n. the state of being heterosexual.
HOMOSEXUALITIEShomosexualities n. Plural of homosexuality.
HOMOSEXUALITY n. the state of being homosexual.
HYDROXYAPATITEShydroxyapatites n. Plural of hydroxyapatite.
HYDROXYAPATITE n. a complex phosphate of calcium that occurs as a mineral and is the chief structural element of vertebrate bone.
HYPEREXCRETIONSHYPEREXCRETION n. excessive excretion.
HYPEREXTENSIONShyperextensions n. Plural of hyperextension.
HYPEREXTENSION n. the extension of a joint beyond its normal range.
LEXICOGRAPHISTSlexicographists n. Plural of lexicographist.
LEXICOGRAPHIST n. one who makes dictionaries.
METHYLXANTHINESmethylxanthines n. Plural of methylxanthine.
METHYLXANTHINE n. a methylated xanthine derivative, such as caffeine, theobromine, or theophylline.
PHOTOOXIDATIONSphotooxidations n. Plural of photooxidation.
PHOTOOXIDATION n. oxidation under the influence of radiant energy, as light.
PHOTOTOXICITIESphototoxicities n. Plural of phototoxicity.
PHOTOTOXICITY n. the state of being phototoxic.
PHYTOTOXICITIESphytotoxicities n. Plural of phytotoxicity.
PHYTOTOXICITY n. the state of being phytotoxic.
PSYCHOSEXUALITYpsychosexuality n. The psychological aspects of sexuality.
PSYCHOSEXUALITY n. the psychic factors of sex.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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