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There are 13 eight-letter words containing H, I, P and X

AMPHIOXIamphioxi n. Plural of amphioxus.
AMPHIOXUS n. (Greek) a fishlike creature, two or three inches long, found in temperate seas, aka lancelet.
ASPHYXIAasphyxia n. Loss of consciousness due to the interruption of breathing and consequent anoxia.
asphyxia n. Loss of consciousness due to the body’s inability to deliver oxygen to its tissues, either by the breathing…
asphyxia n. (Medicine, obsolete) A condition in which an extreme decrease in the concentration of oxygen in the…
FOXSHIPSFOXSHIP n. (Shakespeare) craftiness.
HYPOXIAShypoxias n. Plural of hypoxia.
HYPOXIA n. a deficiency of oxygen in the body tissues, also HYPOXAEMIA, HYPOXEMIA.
OXYPHILEOXYPHILE n. an organism that thrives on an acid environment, also OXYPHIL.
OXYPHILSOXYPHIL n. an organism that thrives on an acid environment, also OXYPHILE.
PHENIXESphenixes n. Plural of phenix.
PHENIX n. a bird fabled to exist single, to be consumed by fire by its own act, and to rise again from its ashes, also PHOENIX.
PHORMINXphorminx n. A kind of lyre used by the Ancient Greeks.
PHORMINX n. (Greek) a kind of lyre used by the Greeks.
PHYLAXISphylaxis n. (Medicine) Protection against infectious disease.
PHYLAXIS n. an inhibiting of infection by the body.
PIXIEISHpixieish adj. Alternative spelling of pixyish.
PIXIEISH adj. like a pixie.
SPHINXESsphinxes n. Plural of sphinx.
sphinxes v. Third-person singular simple present indicative form of sphinx.
SPHINX n. (Greek) any of several Egyptian stone figures of a creature with a human or animal head and (occasionally) breast and a lion's body.
XERAPHINxeraphin n. Alternative form of xeraphim.
XERAPHIN n. (Portuguese) a former silver coin of Goa, also SERAFIN, SERAPHIN, XERAFIN.
XIPHOIDSxiphoids n. Plural of xiphoid.
XIPHOID n. the xiphoid process or xiphisternum.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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